Partner institution: 3:MasarykUniversity-CEITEC
Core facility: Biomolecular Interactions and Crystallization
Category of instrument / technology: Interactions
Web category: 2 : characterisation
Instrument name: BiaCore T200
Description EN:
Biacore T200 is a molecular interaction analysis system monitors real-time, label-free interaction ranging from ions to viruses. The system offers a powerful, versatile solution for obtaining the highest quality kinetic, affinity, concentration, specificity, selectivity, and thermodynamic data and can be used for multiple applications, from early research to drug discovery and development. In the arrangement, one of the interactants is immobilized on the sensor chip surface, while the other is passed over that surface in solution.
Part of research platform:
The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).
Name of instrument operator: Josef Houser
Email of instrument operator: josef.houser@ceitec.muni.cz
Supplier name: AP Czech, s.r.o.
Price (excluding VAT) in EUR: 431566.50
Year of purchase: 2014
Year of installation: 2015
Service contract Yes / No: 0
Yearly price of service contract (excluding VAT) in EUR:
Capacity used in %:
Running cont per hour of usage in EUR: 25
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