Database test

High-end real-time PCR Life Technologies QuantStudio 12k. Available blocks: 96-well Fast, 384-well, TaqMan Array and OpenArray. 

Core Facility Genomics (CFG) offers genomic analysis service and access to up-to-date genomic instrumentation. Main technologies available at the facility are massively parallel sequencing (Illumina), single molecule nanopore sequencing, microarrays and high-throughput & digital PCR. Through cooperation with CEITEC Center of Molecular Medicine it is possible to access other instrumentation – cell sorter, flow cytometers or Laser Capture Microdissection.

System for High-througput qPCR and amplicon sequencing library preparation. Includes Wafergen Multisample Nanodispenser that allows to dispense nanoliter volumes of samples and primers into SmartChips (more than 5.000 reactions), Wafergen SmartCycler for qPCR with SmartChips (2-channel - FAM/SYBRGreen and HEX/VIC) and Wafergen SmartChip TE for amplicon sequencing library preparation using predesigned SmartChip panels.

Core Facility Genomics (CFG) offers genomic analysis service and access to up-to-date genomic instrumentation. Main technologies available at the facility are massively parallel sequencing (Illumina), single molecule nanopore sequencing, microarrays and high-throughput & digital PCR. Through cooperation with CEITEC Center of Molecular Medicine it is possible to access other instrumentation – cell sorter, flow cytometers or Laser Capture Microdissection.

500 MHz NMR spectrometer Bruker Avance for multinuclear applications in liquids and solids, 3 RF channels, equipped with a 5 mm nitrogen-cooled dual (BB-1H) cryoprobe (Prodigy), 5 mm room temperature triple-resonance (1H-13C-15N) probe, 10 mm dual (13C, 1H) probe, and a 4 mm solid-state dual (BB-1H) CP/MAS probe. 

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

600 MHz NMR spectrometer Bruker Avance III HD for high resolution spectroscopy in liquids, 5 RF channels, quadruple-resonance (1H-31P-13C-15N) inverse cryoprobe with cooled 1H and 13C preamplifiers, sample temperature range −40º to 80ºC. 

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

700 MHz NMR spectrometer Bruker Avance III HD for biomolecular applications, 4 RF channels, 5 mm triple-resonance (1H-13C-15N) cryoprobe optimized for 13C detection with cooled 1H, 13C and 15N preamplifiers, sample temperature range −40ºC to 80ºC. 

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

700 MHz NMR spectrometer Bruker Avance III HD for multinuclear applications in liquids and solids, 4 RF channels, equipped with a 5 mm dual broad-band probe, 5 mm dual inverse broad-band probe, 1.7 mm triple resonance (1H-13C-15N) probe, 3.2 mm solid-state triple-resonance (1H-13C-15N) MAS probe, and a 4.0 mm solid-state dual CP/MAS probe. 

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

850 MHz NMR spectrometer Bruker Avance III HD for high resolution spectroscopy in liquids, 4 RF channels, 5 mm triple-resonance (1H/19F-13C-15N) inverse cryoprobe with cooled 1H and 13C preamplifiers, sample temperature range 0ºC to 135ºC

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

950 MHz NMR spectrometer Bruker Avance III HD for high resolution spectroscopy in liquids, 4 RF channels, 5 mm triple-resonance (1H-13C-15N) inverse cryoprobe with cooled 1H and 13C preamplifiers, sample temperature range −40ºC to 80ºC. 

Core Facility of High Field NMR Spectroscopy provides access to NMR spectrometers in the range of proton frequencies from 500 MHz to 950 MHz. The equipment is suited mainly to the studies of structure, dynamics and interactions of biomolecules, i.e. proteins, nucleic acids and carbohydrates. However, the instrumentation is flexible enough to cover also various research needs in material science, organic and inorganic chemistry, biochemistry, biology and biophysics.

256 channels MR compatible EEG system from EGI Net Amps 400 series allows acquisition, review, and analysis of 256 electrodes high density EEG. It provides full scalp coverage for the highest spatial resolution data. Very good resolution is also in temporal domain because sampling frequency is 1 kHz. The system also can be used in MR environments and it is compatible with EEG-TMS. Besides EEG there is a possibility of combination with ExG system and then simultaneous measurement of other signals (ECG, EMG, skin conductance, breathing, movement, general bipolar recording). High density sensor nets allow a simple method to apply dense arrays of sensors quickly and easily in just a few minutes. Use with a simple saline solution for shorter recordings, or a gel for long-term recording. The software Surgical tools can suppress various artefacts (e.g. artefacts from MR scanner recorded during simultaneous measurement with functional magnetic resonance imaging), allow data processing and analysis. Data can be also recorded inside the shielded room. For experiments there is an opportunity to take advantage of equipment for visual and acoustic stimulation and E-Prime stimulation software. 

The laboratory provides modern imaging services, particularly in the area of neuroimaging and human brain mapping, as well as imaging of other parts of human body. MAFIL activities are based on methods such as human MR imaging in a strong magnetic field (including MR spectroscopy) and electrophysiological technique (high-density EEG, simultaneous electrophysiological measurement and MRI). MAFIL expert reports focus mainly on functional and structural brain (head) mapping, because the laboratory was established to serve the needs of neuroscientific research. 

3T, whole-body MRI Scanner has bore size 60cm. XR 80/200 gradient system: 80mT/m & 200t/m/s simultaneously, on all three axes. Simultaneous recording of polygraphic signals (EOG, EKG, EEG, respiration, movement, EMG...). Equipment for fMRI measurements (software for stimulation, audio-visual stimulations in MR...). 

The laboratory provides modern imaging services, particularly in the area of neuroimaging and human brain mapping, as well as imaging of other parts of human body. MAFIL activities are based on methods such as human MR imaging in a strong magnetic field (including MR spectroscopy) and electrophysiological technique (high-density EEG, simultaneous electrophysiological measurement and MRI). MAFIL expert reports focus mainly on functional and structural brain (head) mapping, because the laboratory was established to serve the needs of neuroscientific research.