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Rigaku BioSAXS-1000 SAXS camera for small angle X-ray scattering from solutions of biological macromolecules

X-ray Diffraction and Bio-SAXS core facility is equipped with top-class instruments for diffraction experiments with single crystal samples focused on the determination of the 3-D structure of (macro) molecules down to atomic resolution and for small angle X-ray scattering (SAXS) experiments with isotropically scattering samples focused on determination of the shape and size of macromolecules or nanoparticles. 

Rigaku HighFlux HomeLab™ robotized macromolecular diffraction system with ACTOR sample changer optimized for work at Cu-Kα wavelength

X-ray Diffraction and Bio-SAXS core facility is equipped with top-class instruments for diffraction experiments with single crystal samples focused on the determination of the 3-D structure of (macro) molecules down to atomic resolution and for small angle X-ray scattering (SAXS) experiments with isotropically scattering samples focused on determination of the shape and size of macromolecules or nanoparticles. 

Rigaku HighFlux HomeLab™ universal, dual wavelength (Mo-Kα and Cu-Kα) diffractometer

X-ray Diffraction and Bio-SAXS core facility is equipped with top-class instruments for diffraction experiments with single crystal samples focused on the determination of the 3-D structure of (macro) molecules down to atomic resolution and for small angle X-ray scattering (SAXS) experiments with isotropically scattering samples focused on determination of the shape and size of macromolecules or nanoparticles. 

It is a walk-in plant growth chamber with closed cultivation banks or open shelves. The plant growth chamber enables maintaining controlled growing conditions of temperature and humidity with independent selection of photoperiods. Cultivation banks serve for precisely controlled plant cultivation and comparison studies. Every single bank offers the possibility of different light and temperature regime, which makes them very suitable for multiple or parallel experiments. 

Plant Sciences Core Facility is an open CEITEC laboratory providing access to the research infrastructure for basic plant growth, environmental simulation and phenotyping analyses. The core facility operates 15 fully controlled walk-in growth chambers (phytotrons) and 10 greenhouses to provide defined environment for controlled plant growing. It serves as a focal point for broad-based cutting-edge biological research.

It is a walk-in plant growth chamber with closed cultivation banks or open shelves. The plant growth chamber enables maintaining controlled growing conditions of temperature and humidity with independent selection of photoperiods. Cultivation banks serve for precisely controlled plant cultivation and comparison studies. Every single bank offers the possibility of different light and temperature regime, which makes them very suitable for multiple or parallel experiments. 

Plant Sciences Core Facility is an open CEITEC laboratory providing access to the research infrastructure for basic plant growth, environmental simulation and phenotyping analyses. The core facility operates 15 fully controlled walk-in growth chambers (phytotrons) and 10 greenhouses to provide defined environment for controlled plant growing. It serves as a focal point for broad-based cutting-edge biological research.

VP-DSC is differential scanning microcalorimeter with 500 µl volume of sample cell. DSC technique measures heat changes that occur in the (bio)molecule sample solution during a controlled increase or decrease in temperature, on the basis of a temperature difference between the sample and the reference material.

The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).

older system purchased before the CEITEC establishment

Fully automated isothermal calorimeter AutoITC200 with ultrasmall working cell (200 µl). ITC method is used for characterization of biomolecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and others. Enzyme kinetics, biological activity or the effect of molecular structure changes on binding mechanism can be also assessed. Complete thermodynamic profile of the molecular interaction in a single experiment (stoichiometry, Ka, ∆H and ∆S values).

The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).

Biacore T200 is a molecular interaction analysis system monitors real-time, label-free interaction ranging from ions to viruses. The system offers a powerful, versatile solution for obtaining the highest quality kinetic, affinity, concentration, specificity, selectivity, and thermodynamic data and can be used for multiple applications, from early research to drug discovery and development. In the arrangement, one of the interactants is immobilized on the sensor chip surface, while the other is passed over that surface in solution.

The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).

CD spectrometer Jasco J-815 can measure circular dichroism, fluorescence, total fluorescence, linear dichroism, magnetic dichroism, optical rotation dispersion, and stopped flow circular dichroism, fluorescence and absorbance.

The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).

Automated high throughput protein crystal drop imaging system provides ultraviolet and visible crystal imaging and protein crystal monitoring that automatically image crystallization experiments and link images with crystallization conditions.Automated system contains fully integrated system for temperature controlled incubation, inspection, and analysis of protein crystallization plates.

The core facility provides services leading to biophysical and structure characterization of biomolecules and to study (bio)molecular interactions.  It is equipped with the instrumentation to set up crystallization conditions of biomolecules and their complexes, basic characterization of physical properties of the molecules (analytical ultracentrifugation, dynamic light scattering, CD spectroscopy, differential scanning calorimetry, differential scanning fluorimetry), and to study thermodynamics and/or kinetics of interactions (isothermal titration calorimetry, surface plasmon resonance, microscale thermophoresis, CD spectroscopy, analytical ultracentrifugation).